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Thu. 17 Aug, 2023

UPSC Seminar: Sebastian Marquardt

Thu. 17 Aug, 2023 10:00 - 11:00
UPSC Seminar

Sebastian Marquardt
Section for Molecular Plant Biology, Department of Plant and Environmental Sciences, University of Copenhagen

Title: Languages of the Non-coding Genome

Host: Stephan Wenkel


Genomes are the blueprints of life: the genomic DNA sequences contain the instructions for the formation of a given species. DNA sequence polymorphisms between individuals of the same species offer a hypothesis to understand the molecular bases of fitness differences. However, many polymorphisms are located in parts of the genome that we poorly understand: the non-coding genome. While polymorphisms that change the protein sequence offer a sufficiently clear path forward, my seminar outlines approaches and solutions to understand the non-coding genome.
Results from my laboratory illustrate different molecular mechanisms of how the non-coding genome promotes organismal fitness. The results from my lab highlight different ways of how the non-coding genome communicates functional information, with intriguing implications for current models explaining non-coding genome conservation and function.

More information about Sebastian Marquardt's research