Research
In my research group, we use machine learning methods and large-scale genomics datasets to model how genes interact in regulatory networks, how regulatory networks evolve and how they give rise to complex properties characteristic to individuals and species.
Our main project aims to understand the process of wood formation in angiosperm and gymnosperm tree species by modelling the regulatory networks orchestrating the differentiation of stem cells into woody tissues. To this end, we are integrating large-scale multi-omics data to infer regulatory networks for several species and comparing these networks across species to identify regulatory mechanisms explaining the evolution of trees.
In another project, we work to understand how gene regulation evolves after whole genome duplication and to reveal to what degree these events, which play major roles in plant evolution, spark new regulatory innovations. To this end, we are developing phylogenetic methods for comparative analysis of omics data across multiple species.
In collaboration with Nathaniel Street, we are developing a number of online tools for facilitating comparative network analysis in plants. ComPlEx, available through the PlantGenIE portal (http://plantgenie.org), allows Comparative analysis of Plant Expression networks. AspWood (http://aspwood.popgenie.org) and NorWood (http://norwood.congenie.org) offer dedicated tools to analyze high-resolution gene expression data across wood formation in aspen and Norway spruce.
Contact
Torgeir R. Hvidsten
Professor and BIAS group leader
Norwegian University of Life Sciences
Email:
Main homepage: http://www.trhvidsten.org/
Twitter: https://twitter.com/TRHvidsten
CV T. R. Hvidsten
Education
- 2012: Docent, Umeå University (UmU), Umeå, Sweden
- 2004: PhD, Linnaeus Centre for Bioinformatics, Uppsala University (UU), Sweden
- 2000: MSc, Norwegian University of Science and Technology (NTNU), Norway
Positions
- Since 2012: Professor, Norwegian University of Life Sciences (NMBU), Norway
- 2012-2018: Guest professor, Umeå Plant Science Centre, Umeå University, Sweden
- 2008-2012: Assistant professor, Umeå Plant Science Centre, Umeå University, Sweden
- 2004-2008: Postdoc/Researcher, Linnaeus Centre for Bioinformatics, Uppsala University, Sweden