My research group is focused on understanding how plants are adapted to the environment in which they occur. We are interested in determining the actual genes involved in conferring local adaptation and how genetic variation in these genes has been shaped by evolutionary processes, such as natural selection and genetic drift.
Ingvarsson Par 1150 766
per_1The large poplar long- horned beetle (Saperda carcharias) is one of the many insects that occur on European aspen (Populus tremula) in Sweden. The larvae feed on the inner bark, sapwood and heartwood and can result in significant tree mortality, especially in young shoots.The genetic basis of local adaptation
Natural selection can lead to genetic differentiation between populations for adaptive traits, even in the presence of substantial migration. A classic example in forest trees is adaptation to the steep latitudinal gradient in the length of growing season that characterizes northern environments. Trees often show latitudinal clines in traits, such as the timing of bud set, the onset of flowering and frost hardening. We are investigating the genetic basis of phenological traits that are responsible for climatic adaptations in European aspen (Populus tremula). We are using a collection of P. tremula genotypes (the SwAsp collection) to infer the genetic basis of phenology traits along a latitudinal gradient across Sweden. We are using a combination of association mapping techniques and molecular population genetic studies to link variation in candidate genes to naturally occurring variation in phenology.

The genetic basis of plant defence
Plants have evolved numerous adaptations to defend themselves against attack by herbivores and my group is also studying the genetic basis of plant resistance using the SwAsp collection. We are currently inferring historical patterns of evolution of genes involved in herbivore defence using molecular population genetic methods and using association mapping to dissect naturally occurring variation in herbivore resistance in the SwAsp collection. Many important phenotypic adaptations are mediated by changes in gene regulation, rather than through changes in protein coding sequences, and we are also investigating genes involved in signal transduction pathways that induce wound responses in P. tremula.
sweden_greySvensk sammanfattning

Publications list

  1. Functional and evolutionary genomic inferences in Populus through genome and population sequencing of American and European aspen
    Proc Natl Acad Sci U S A. 2018, 115(46):E10970-E10978
  2. A major locus controls local adaptation and adaptive life history variation in a perennial plant
    Genome Biol. 2018 Jun 4;19(1):72
  3. Storage lipid accumulation is controlled by photoperiodic signal acting via regulators of growth cessation and dormancy in hybrid aspen
    New Phytol. 2018, 219 (2):619-630
  4. Genomic relationships reveal significant dominance effects for growth in hybrid Eucalyptus
    Plant Sci. 2018, 267:84-93
  5. BatchMap: A parallel implementation of the OneMap R package for fast computation of F-1 linkage maps in outcrossing species
    PLOS ONE 2017, 12 (12)
  6. Evaluating the accuracy of genomic prediction of growth and wood traits in two Eucalyptus species and their F1 hybrids
    BMC Plant Biol. 2017, 17(1):110
  7. Small- and large-scale heterogeneity in genetic variation across the collard flycatcher genome: implications for estimating genetic diversity in nonmodel organisms
    Mol Ecol Resour. 2017 Jul;17(4):583-585
  8. Autumn senescence in aspen is not triggered by day length
    Physiol Plant. 2018, 162(1):123-134
  9. Gene co-expression network connectivity is an important determinant of selective constraint
    PLoS Genet. 2017, 13(4):e1006402
  10. Natural Selection and Recombination Rate Variation Shape Nucleotide Polymorphism Across the Genomes of Three Related Populus Species
    GENETICS 2016, 202 (3):1185
  11. Whole genome duplication in coast redwood (Sequoia sempervirens) and its implications for explaining the rarity of polyploidy in conifers
    New Phytol. 2016, 211(1):186-193
  12. Variation in linked selection and recombination drive genomic divergence during allopatric speciation of European and American aspens
    Mol Biol Evol. 2016, 33(7):1754-1767
  13. Multilocus Analysis of Nucleotide Variation and Speciation in Three Closely Related Populus (Salicaceae) Species
    Mol Ecol. 2015, 24(19):4994-5005
  14. Genetic architecture and genomic patterns of gene flow between hybridizing species of Picea
    Heredity (Edinb). 2015, 115(2):153-64
  15. Genome-wide analysis reveals diverged patterns of codon bias, gene expression and rates of sequence evolution in Picea gene families
    Genome Biol Evol. 2015, 7(4):1002-1015
  16. Identification of additive, dominant, and epistatic variation conferred by key genes in cellulose biosynthesis pathway in Populus tomentosa
    DNA Res. 2015, 22(1):53-67
  17. Insights into Conifer Giga-Genomes
    Plant Physiol. 2014, 166(4):1724-32
  18. Populus tremula (European aspen) shows no evidence of sexual dimorphism
    BMC Plant Biol. 2014; 14(1):276
  19. Increased genetic divergence between two closely related fir species in areas of range overlap
    Ecol Evol. 2014; 4(7):1019-1029
  20. The Norway spruce genome sequence and conifer genome evolution
    Nature 2013; 497(7451):579-584
  21. Geographic structure in metabolome and herbivore community co-occurs with genetic structure in plant defence genes
    Ecology Letters 2013, 16 (6):791-798
  22. Klintenäs M, Pin PA, Benlloch R, Ingvarsson PK, Nilsson O
    Analysis of conifer FLOWERING LOCUS T/TERMINAL FLOWER1-like genes provides evidence for dramatic biochemical evolution in the angiosperm FT lineage
    New Phytol. 2012, 196(4):1260-1273
  23. Robinson KM, Ingvarsson PK, Jansson S, Albrectsen BR
    Genetic Variation in Functional Traits Influences Arthropod Community Composition in Aspen (Populus tremula L.)
    PLoS ONE 2012; 7(5):e37679
  24. Ismail M, Soolanayakanahally RJ, Ingvarsson PK, Guy RD , Jansson S, Silim SN, El-Kassaby YA
    Comparative Nucleotide Diversity Across North American and European Populus Species
    Journal of Molecular Evolution 2012 74(5-6): 257-272
  25. Bernhardsson C, Ingvarsson PK
    Geographical structure and adaptive population differentiation in herbivore defence genes in European aspen (Populus tremula L., Salicaceae)
    Mol Ecol. 2012 Mar 15
  26. Bernhardsson C, Ingvarsson PK
    Molecular Population Genetics of Elicitor-Induced Resistance Genes in European Aspen (Populus tremula L., Salicaceae)
    PLoS One. 2011;6(9):e24867. Epub 2011 Sep 19.
  27. Lind MI, Ingvarsson PK, Johansson H, Hall D, Johansson F
    Gene flow and selection on phenotypic plasticity in an island system of Rana temporaria
    Evolution: 2011 65:684-697
  28. Hall D, Ma XF, Ingvarsson PK
    Adaptive evolution of the Populus tremula photoperiod pathway
    Molecular Ecology: 2011 20:1463-1474
  29. Ingvarsson PK, Street NR
    Association genetics of complex traits in plants
    New Phytologist: 2011 189:909-922
  30. Ma X-F, Hall D, St. Onge KR, Jansson S, Ingvarsson PK
    Genetic differentiation, clinal variation and phenotypic associations with growth cessation across the Populus tremula photoperiodic pathway
    Genetics: 2010 186:1033-1044
  31. Jansson S, Ingvarsson PK
    Cohort-structured tree populations
    Heredity 2010 105:331-332
  32. Hall D, Tegström C, Ingvarsson PK
    Using association mapping to dissect the genetic basis of complex traits in plants
    Briefings in Functional Genomics: 2010 9:157-165
  33. De Carvalho D, Ingvarsson PK, Joseph J, Suter L, Sedivy C, Macaya-Sanz D, Cottrell J, Heinze B, Schanzer I, Lexer C
    Admixture facilitates adaptation from standing variation in the European aspen (Populus tremula L.), a widespread forest tree
    Molecular Ecology: 2010 19: 1638-1650
  34. Ingvarsson PK
    Natural selection on synonymous and non-synonymous mutations shape patterns of polymorphism in Populus tremula
    Molecular Biology and Evolution: 2010 27:650-660
  35. Ingvarsson PK
    Molecular evolution of synonymous codon usage in Populus
    BMC Evolutionary Biology: 2008 8:307
  36. Ingvarsson PK
    Multilocus patterns of nucleotide polymorhism and the deomographic history of Populus tremula
    Genetics: 2008 180:329-340
  37. Ingvarsson PK, Garcia MV, Luquez V, Hall D, Jansson S
    Nucleotide polymorphism and phenotypic associations within and around the phytochrome B2 locus in European aspen (Populus tremula, Salicaceae)
    Genetics: 2008 178:2217-2226
  38. Neale DB, Ingvarsson PK
    Population, quantitative and comparative genomics of adaptation in forest trees
    Current Opinion in Plant Biology: 200811:149-155
  39. Hall D, Luquez V, Garcia VM, St Onge KR, Jansson S, Ingvarsson PK
    Adaptive population differentiation in phenology across a latitudinal gradient in European aspen (Populus tremula, L.): A comparison of neutral markers, candidate genes and phenotypic traits
    Evolution: 2007 61:2849-2860
  40. Luquez V, Hall D, Albrectsen BR, Karlsson J, Ingvarsson P, Jansson S
    Natural phenological variation in aspen (Populus tremula): the SwAsp collection
    Tree Genetics & Genomes: 2008 4:279-292
  41. Garcia MV, Ingvarsson PK
    An excess of nonsynonymous polymorphism and extensive haplotype structure at the PtABI1B locus in European aspen (Populus tremula): a case of balancing selection in an obligately outcrossing plant?
    Heredity: 2007:1-6
  42. Barr CM, Keller SR, Ingvarsson PK, Sloan DB, Taylor DR
    Variation in mutation rate and polymorphism among mitochondrial genes of Silene vulgaris
    Molecular Biology and Evolution: 2007 24:1783-1791
  43. Ingvarsson PK
    Gene expression and protein length influence codon usage and rates of sequence evolution in Populus tremula
    Molecular Biology and Evolution: 2007 24:836-844.
  44. Ingvarsson PK, Garcia MV, Hall D, Luquez V, Jansson S
    Clinal variation in phyB2, a candidate gene for day-length-induced growth cessation and bud set, across a latitudinal gradient in European aspen (Populus tremula)
    Genetics: 2006 172:1845-1853
  45. Talyzina NM, Ingvarsson PK
    Molecular evolution of a small gene family of wound inducible Kunitz trypsin inhibitors in Populus
    Journal of Molecular Evolution: 2006 63:108-119
  46. Ingvarsson PK
    Molecular population genetics of herbivore-induced protease inhibitor genes in European aspen (Populus tremula L., Salicaceae)
    Mol Biol Evol: 2005 22:1802-1812
  47. Ingvarsson PK
    Nucleotide polymorphism and linkage disequilbrium within and among natural populations of European Aspen (Populus tremula L., Salicaceae)
    Genetics: 2005 169:945-953
  48. Ingvarsson PK
    Population subdivision and the Hudson-Kreitman-Aguade test: testing for deviations from the neutral model in organelle genomes
    Genet Res: 2004 83:31-39
  49. Taylor DR, Ingvarsson PK
    Common features of segregation distortion in plants and animals
    Genetica: 2003 117:27-35
  50. Ingvarsson PK, Ribstein S, Taylor DR
    Molecular evolution of insertions and deletion in the chloroplast genome of silene
    Mol Biol Evol: 2003 20:1737-1740
  51. Ingvarsson PK
    A metapopulation perspective on genetic diversity and differentiation in partially self-fertilizing plants
    Evolution Int J Org Evolution: 2002 56:2368-2373
  52. Ingvarsson PK
    Conservation biology - Lone wolf to the rescue
    Nature: 2002 420:472-472
  53. Ingvarsson PK, Taylor DR
    Genealogical evidence for epidemics of selfish genes
    Proc Natl Acad Sci U S A: 2002 99:11265-11269
  54. Ingvarsson PK
    Restoration of genetic variation lost - The genetic rescue hypothesis
    Trends in Ecology & Evolution: 2001 16:62-63
  55. Ingvarsson PK
    Differential migration from high fitness demes in the shining fungus beetle, Phalacrus substriatus
    Evolution Int J Org Evolution: 2000 54:297-301
  56. Ingvarsson PK, Ericson L
    Exploitative competition between two seed parasites on the common sedge, Carex nigra
    Oikos: 2000 91:362-370
  57. Ingvarsson PK, Whitlock MC
    Heterosis increases the effective migration rate
    Proceedings of the Royal Society of London Series B-Biological Sciences: 2000 267:1321-1326
  58. Moen J, Ingvarsson PK, Walton DWH
    Estimates of structural complexity in clonal plant morphology: comparisons of grazed and ungrazed Acaena magellanica rhizomes
    Canadian Journal of Botany-Revue Canadienne De Botanique: 1999 77:869-876
  59. Ingvarsson PK
    Group selection in density-regulated populations revisited
    Evolutionary Ecology Research: 1999 1:527-536
  60. Ingvarsson PK, Giles BE
    Kin-structured colonization and small-scale genetic differentiation in Silene dioica
    Evolution: 1999 53:605-611
  61. Carlsson-Graner U, Elmqvist T, Agren J, Gardfjell H, Ingvarsson P
    Floral sex ratios, disease and seed set in dioecious Silene dioica
    Journal of Ecology: 1998 86:79-91
  62. Lundberg S, Ingvarsson PK
    Population dynamics of resource limited plants and their pollinators
    Theor Popul Biol: 1998 54:44-49
  63. Ingvarsson PK, Ericson L
    Spatial and temporal variation in disease levels of a floral smut (Anthracoidea heterospora) on Carex nigra
    Journal of Ecology: 1998 86:53-61
  64. Ingvarsson PK, Olsson K, Ericson L
    Extinction-recolonization dynamics in the mycophagous beetle Phalacrus substriatus
    Evolution: 1997 51:187-195
  65. Ingvarsson PK, Olsson K
    Hierarchical genetic structure and effective population sizes in Phalacrus substriatus
    Heredity: 1997 79:153-161
  66. Ingvarsson PK
    The effect of delayed population growth on the genetic differentiation of local populations subject to frequent extinctions and recolonizations
    Evolution: 1997 51:29-35
  67. Folgarait PJ, Marquis RJ, Ingvarsson P, Braker HE, Arguedas M
    Patterns of attack by insect herbivores and a fungus on saplings in a tropical tree plantation
    Environmental Entomology: 1995 24:1487-1494
  68. Ingvarsson PK, Lundberg S
    Pollinator Functional-Response and Plant-Population Dynamics - Pollinators as a Limiting Resource
    Evolutionary Ecology: 1995 9:421-428
  69. Ingvarsson PK, Lundberg S
    The Effect of a Vector-Borne Disease on the Dynamics of Natural Plant-Populations - a Model for Ustilago-Violacea Infection of Lychnis-Viscaria
    Journal of Ecology: 1993 81:263-270